METTL2A Antibody, Biotin conjugated

Code CSB-PA856955LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) METTL2A Polyclonal antibody
Uniprot No.
Target Names
METTL2A
Alternative Names
METTL2A antibody; METTL2 antibody; HSPC266 antibody; tRNA N(3)-methylcytidine methyltransferase METTL2A antibody; EC 2.1.1.- antibody; Methyltransferase-like protein 2A antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Methyltransferase-like protein 2A protein (1-242AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU).
Gene References into Functions
  1. Data, including data from studies using mutant/knockout mice and cell lines from such mice, suggest that METTL2 and METTL6 (but not METTL8) contribute to post-transcriptional methylation of cytidine (formation of 3-methylcytidine) in tRNA; METTL2 methylates tRNA(Thr) and tRNA(Arg); METTL6 interacts with seryl-tRNA synthetase and methylates tRNA(Ser); METTL8 catalyzes post-transcriptional methylation of cytidine in mRNA. PMID: 28655767
Protein Families
Methyltransferase superfamily, METL family
Database Links

HGNC: 25755

OMIM: 607846

KEGG: hsa:339175

STRING: 9606.ENSP00000309610

UniGene: Hs.381204

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